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In future, commercial attractiveness is expected to become more of a key consideration for drug R&D
LEK · 2022 · industry_trends
In future, commercial attractiveness is expected to become more of a key consideration for drug R&D
 Respondents also think that commercial attractiveness related factors are quite important when making comprehensive considerations for drug prioritization
LEK · 2022 · key_takeaways
Respondents also think that commercial attractiveness related factors are quite important when making comprehensive considerations for drug prioritization
85 — Percent of respondents
 Oncology, immunology & rheumatology, rare diseases and CNS are perceived of high commercial attractiveness by respondents in the next 5 years
LEK · 2022 · industry_trends
Oncology, immunology & rheumatology, rare diseases and CNS are perceived of high commercial attractiveness by respondents in the next 5 years
6.4 — Average score
 Other factors considered for drug prioritization include return on investment, company expertise, and feasibility to collaborate
LEK · 2022 · other
Other factors considered for drug prioritization include return on investment, company expertise, and feasibility to collaborate
 Increasing complexity is the mega trend of clinical trial, driving the needs for smart and digital technologies
LEK · 2022 · industry_trends
Increasing complexity is the mega trend of clinical trial, driving the needs for smart and digital technologies
 Clinical trial digitalization has experienced rapid evolution over the past 7-8 years, and has been calling for platforms & integration to further improve trial quality and efficiency
LEK · 2022 · timeline
Clinical trial digitalization has experienced rapid evolution over the past 7-8 years, and has been calling for platforms & integration to further improve trial quality and efficiency
 EDC, CTMS, eTMF and PVS technologies are being widely adopted in China clinical trials
LEK · 2022 · industry_trends
EDC, CTMS, eTMF and PVS technologies are being widely adopted in China clinical trials
76% — Percent of respondents
 Majority of respondents believe smart and digital tools will be indispensable with increasing demand of smart trials, and 33% even believe that revolutionary impact will be brought in next 10 years
LEK · 2022 · key_takeaways
Majority of respondents believe smart and digital tools will be indispensable with increasing demand of smart trials, and 33% even believe that revolutionary impact will be brought in next 10 years
71% — respondent agreement
 Nearly half of the respondents also believe there will be increasing data interaction needs and emergence of new smart trial format going forward
LEK · 2022 · industry_trends
Nearly half of the respondents also believe there will be increasing data interaction needs and emergence of new smart trial format going forward
52 — Percent of respondents
 Virtual trial / DCT: Virtual clinical trial has indeed become a heated topic, which has also obtained attention from regulatory authority recently
LEK · 2022 · timeline
Virtual trial / DCT: Virtual clinical trial has indeed become a heated topic, which has also obtained attention from regulatory authority recently
 Virtual trial / DCT: There exist both drivers and barriers for the future development of virtual clinical trial with efficiency improvement as main driver and policy uncertainty as main concern
LEK · 2022 · framework_other
Virtual trial / DCT: There exist both drivers and barriers for the future development of virtual clinical trial with efficiency improvement as main driver and policy uncertainty as main concern
 Virtual trial / DCT: Respondents also show split attitude on likelihood to conduct virtual trial / DCT in China, with ability to live monitor trial data as key rationale for adoption
LEK · 2022 · industry_trends
Virtual trial / DCT: Respondents also show split attitude on likelihood to conduct virtual trial / DCT in China, with ability to live monitor trial data as key rationale for adoption
79% — Percent of respondents
 Globalization of Chinese biopharma and the evolution of MNC China R&D strategy are also the two noteworthy trends of clinical trial development in China
LEK · 2022 · industry_trends
Globalization of Chinese biopharma and the evolution of MNC China R&D strategy are also the two noteworthy trends of clinical trial development in China
 Globalization is increasingly an imperative for Chinese biopharmas with 95% of respondents either conducted or expressed interest in ex-China clinical trials
LEK · 2022 · industry_trends
Globalization is increasingly an imperative for Chinese biopharmas with 95% of respondents either conducted or expressed interest in ex-China clinical trials
95% — Percent of respondents
 U.S., Australia and Europe are the most attractive destinations outside China for Chinese biopharmas, considering MNC collaboration, clinical trial duration and speed-to-market
LEK · 2022 · market_landscape
U.S., Australia and Europe are the most attractive destinations outside China for Chinese biopharmas, considering MNC collaboration, clinical trial duration and speed-to-market
81 — Percent of respondents
 In order to succeed in oversea clinical trial, careful prioritization of destination, oversea local team setup, and active communication with regulatory agencies are anticipated
LEK · 2022 · key_takeaways
In order to succeed in oversea clinical trial, careful prioritization of destination, oversea local team setup, and active communication with regulatory agencies are anticipated
 Chinese innovations are now being validated on the international stage, as their global rights are being picked up by oversea counterparts ...
LEK · 2022 · industry_trends
Chinese innovations are now being validated on the international stage, as their global rights are being picked up by oversea counterparts ...
 ... among which leading international pharma are actively licensing in Chinese innovative assets
LEK · 2022 · precedent
... among which leading international pharma are actively licensing in Chinese innovative assets
2,940 — Deal size (USD Mn)
 MNCs are shifting from establishing China R&D centers to China partnership centers or incubation centers to facilitate the collaboration with Chinese biopharmas
LEK · 2022 · timeline
MNCs are shifting from establishing China R&D centers to China partnership centers or incubation centers to facilitate the collaboration with Chinese biopharmas
 Majority of respondents believe that MNC will further strengthen the partnerships with Chinese companies through investment and incubation
LEK · 2022 · key_takeaways
Majority of respondents believe that MNC will further strengthen the partnerships with Chinese companies through investment and incubation
58% — Percent of respondents
 Industry can support and lead this China clinical trial transformation
LEK · 2022 · next_steps
Industry can support and lead this China clinical trial transformation
 We have also leveraged a wide range of secondary sources and L.E.K.’s China healthcare knowledge base
LEK · 2022 · appendix
We have also leveraged a wide range of secondary sources and L.E.K.’s China healthcare knowledge base
 L.E.K. would like to acknowledge our co-sponsor – PharmaDJ’s great contribution for this report
LEK · 2022 · other
L.E.K. would like to acknowledge our co-sponsor – PharmaDJ’s great contribution for this report
 L.E.K. Consulting is a global strategy consulting firm with significant coverage in healthcare
LEK · 2022 · other
L.E.K. Consulting is a global strategy consulting firm with significant coverage in healthcare
~1700 — staff
 Defining boundaries of the Media and Entertainment sector
misc · 2012 · segmentation
Defining boundaries of the Media and Entertainment sector
 Filmed production industry direct spend has increased 70% since 2002. Employment grew by over 30k since 2004.
misc · 2012 · situation_overview
Filmed production industry direct spend has increased 70% since 2002. Employment grew by over 30k since 2004.
$7.1bn — Direct spend
 NYC filmed entertainment industry growth impressive in face of nationwide decline
misc · 2012 · industry_trends
NYC filmed entertainment industry growth impressive in face of nationwide decline
20% — Job growth
 NYC television production has doubled since 2002, now accounting for $3b in spend and employing ~30k people
misc · 2012 · market_sizing
NYC television production has doubled since 2002, now accounting for $3b in spend and employing ~30k people
$3b — Total NYC spend
 NYC film production is at its highest levels supporting employment of over 12k¹ and $1.4b in direct spend
misc · 2012 · market_landscape
NYC film production is at its highest levels supporting employment of over 12k¹ and $1.4b in direct spend
$1.4b — Direct spend
 TV commercials still drive $420M in spend and employ 5k people¹; other filmed production employs another 1k+
misc · 2012 · market_sizing
TV commercials still drive $420M in spend and employ 5k people¹; other filmed production employs another 1k+
$420M — Total Spend
 Production related activities are also an important source of jobs in NYC, employing over 45k¹ additional people
misc · 2012 · market_landscape
Production related activities are also an important source of jobs in NYC, employing over 45k¹ additional people
45k — Total NYC FTEs
 Strong cable growth has offset broadcasting slowdown, as lines between industries continue to blur
misc · 2012 · industry_trends
Strong cable growth has offset broadcasting slowdown, as lines between industries continue to blur
$20bn — NYC revenue
 NYC media sector currently accounts for ~ 275k jobs and generates revenues of ~$80bn
misc · 2012 · market_landscape
NYC media sector currently accounts for ~ 275k jobs and generates revenues of ~$80bn
$80bn — NYC media sector revenue
 In face of nationwide traditional media slowdown, NYC has been growing and gaining substantial national share
misc · 2012 · market_landscape
In face of nationwide traditional media slowdown, NYC has been growing and gaining substantial national share
10.8% — NYC jobs/total US jobs
 Publishing revenues flat and jobs in decline as traditional advertising revenues quickly drop
misc · 2012 · industry_trends
Publishing revenues flat and jobs in decline as traditional advertising revenues quickly drop
9k — NYC FTEs
 Advertising agencies have successfully managed shift to digital and posted growth in all years except for 2009
misc · 2012 · industry_trends
Advertising agencies have successfully managed shift to digital and posted growth in all years except for 2009
16% — NYC advertising revenue
 Between start-up boom and increased presence of big tech, NYC digital sector has exhibited strong growth
misc · 2012 · industry_trends
Between start-up boom and increased presence of big tech, NYC digital sector has exhibited strong growth
25.0 — Digital FTEs
 Media VC has exploded in NYC over the past 10 years
misc · 2012 · market_landscape
Media VC has exploded in NYC over the past 10 years
$591M — VC investment
 In particular, the past four years have shaped much of NYC's digital and technology landscape
misc · 2012 · timeline
In particular, the past four years have shaped much of NYC's digital and technology landscape
 Interviewees highlighted several NYC advantages that the city should seek to leverage
misc · 2012 · key_messages
Interviewees highlighted several NYC advantages that the city should seek to leverage
 ...but also recognized some areas of concern that the city should try to mitigate
misc · 2012 · pain_points
...but also recognized some areas of concern that the city should try to mitigate
 Subsector-specific trends hold varying implications on NYC
misc · 2012 · industry_trends
Subsector-specific trends hold varying implications on NYC
 Given sector trends, future NYC media growth will come from start-ups, digital, and post production areas
misc · 2012 · strategic_options
Given sector trends, future NYC media growth will come from start-ups, digital, and post production areas
 Media leader interviews indentify four main areas for development across subsectors
misc · 2012 · key_messages
Media leader interviews indentify four main areas for development across subsectors
 Some of these areas are already being addressed by several NYC Government initiatives and new programs...
misc · 2012 · initiative_list
Some of these areas are already being addressed by several NYC Government initiatives and new programs...
 New ideas were proposed on media sector promotion, some of which could use the collaboration of media leaders
misc · 2012 · initiative_list
New ideas were proposed on media sector promotion, some of which could use the collaboration of media leaders
 Additionally, various media leaders have own programs underway that NYC could help support and publicize
misc · 2012 · initiative_list
Additionally, various media leaders have own programs underway that NYC could help support and publicize
 NYC media leaders also highlighted need to expand scope of talent efforts and praised the Engineering campus effort
misc · 2012 · framework_other
NYC media leaders also highlighted need to expand scope of talent efforts and praised the Engineering campus effort
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